Oxidative Stress Profile By Vibrant Wellness USA
The Oxidative Stress Profile is a urine and saliva test that evaluates oxidative damage, antioxidant capacity, and cellular resilience, key factors in understanding the biological rate of aging and foundational elements of longevity. Using advanced liquid chromatography–mass spectrometry (LC-MS/MS), the test measures 16 urinary markers of oxidative damage to DNA, RNA, proteins, and lipids. It also analyzes 32 antioxidant-related genetic variants via RT-PCR to assess your inherited capacity to neutralize free radicals. This test provides clinical insight into free radical activity, inflammation, and mitochondrial function, helping guide targeted strategies to reduce oxidative stress and support long-term cellular health.
What We Measure
- Extensive Evaluation of Oxidative Damage measures markers related to free radical activity, mitochondrial dysfunction, and antioxidant capacity, offering deeper insights into cellular health than standard tests.
- Advanced LC-MS/MS Technology provides precise detection of oxidative stress biomarkers, allowing for accurate assessment of inflammation and cellular damage.
- Guided Detox Strategies helps reduce oxidative damage and improve mitochondrial function through targeted antioxidant and detoxification protocols.
- Long-Term Wellness Optimization supports overall health by identifying oxidative stress as a root cause of chronic diseases, providing a foundation for personalized wellness strategies.
You may benefit from this test if you have:
- PRKAA2: rs2796498, rs10789038
- CAT (Catalase): rs1001179, rs7943316, rs4756146
- COX-2: rs20417
- CYB5R3: rs916321
- CYP1A1: rs1048943
- GLUL: rs10911021
GPX (Glutathione Peroxidase):
- GPX1: rs1050450, rs1987628
- GPX2: rs4902346, rs2071566
- GPX4: rs713041
GSTM (Glutathione S-Transferase):
- GSTM1: rs366631
- GSTM5: rs3754446
- GSTP1: rs1695
- GSS (Glutathione Synthetase): rs121909307
- GSR (Glutathione Reductase): rs8190955
- HMOX1 (Heme Oxygenase 1): rs2071746
- CYBA (Cytochrome B-245 Alpha Chain): rs4673, rs9932581
- SELENOP (Selenoprotein P): rs3877899
SOD (Superoxide Dismutase):
- SOD1: rs2234694
- SOD2: rs4880
- SOD3: rs1799895, rs8192287
TXNRD (Thioredoxin Reductase):
- TXNRD1: rs7310505
- TXNRD2: rs1548357
- TRXR2: rs4485648
- XDH (Xanthine Dehydrogenase): rs206812, rs2073316
Lipid Peroxidation Markers
- Malondialdehyde (MDA)
- Glutathione 4-Hydroxynonenal (GS-HNE)
- 8-Iso-Prostaglandin F2α (8-iso-PGF2α)
- 11-β-Prostaglandin F2α
- 15(R)-Prostaglandin F2α
Protein Oxidation Markers
- Dityrosine
- 3-Bromotyrosine
- 3-Chlorotyrosine
DNA Damage Markers
- 8-Hydroxy-2-Deoxyguanosine (8-OHdG)
- 8-Hydroxyguanine
- 8-Hydroxyguanosine
Nitrative Stress Biomarkers
- 8-Nitroguanosine
- 8-Nitroguanine
- Nitrotyrosine
- Nε-(Carboxymethyl) Lysine (CML)
- Nε-Carboxyethyllysine (CEL)
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